Myeloid-derived suppressor cells regulate T cell and B cell responses during autoimmune disease

MDSCs are a heterogeneous group of myeloid cells that suppress T cell activity in cancer and autoimmune disease. The effect of MDSCs on B cell function is not clear. Using the CIA model of autoimmune disease, we found an increase in M-MDSCs in the periphery of WT mice with CIA compared with naïve mi...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Crook, Kristen R., Jin, Mengyao, Weeks, Michael F., Rampersad, Rishi R., Baldi, Robert M., Glekas, Amy S., Shen, Yajuan, Esserman, Denise A., Little, Paul, Schwartz, Todd A., Liu, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2015
Assuntos:
Host Defense & Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338846/
https://ncbi.nlm.nih.gov/pubmed/25583578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A0314-139R
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