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Improved molecular diagnosis by the detection of exonic deletions with target gene capture and deep sequencing

PURPOSE: We aimed to demonstrate the detection of exonic deletions using target capture and deep sequencing data. METHODS: Sequence data from target gene capture followed by massively parallel sequencing were analyzed for the detection of exonic deletions using the normalized mean coverage of indivi...

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Detalhes bibliográficos
Publicado no:Genet Med
Main Authors: Feng, Yanming, Chen, David, Wang, Guo-Li, Zhang, Victor Wei, Wong, Lee-Jun C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338802/
https://ncbi.nlm.nih.gov/pubmed/25032985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2014.80
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