Synthesis of an anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell line

Anthraquinones are an important class of naturally occurring biologically active compounds. In this study, anthraquinone derivative 1,3-dihydroxy-9,10-anthraquinone-2- carboxylic acid (DHAQC) (2) was synthesized with 32% yield through the Friedel–Crafts condensation reaction. The mechanisms of cytot...

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Détails bibliographiques
Publié dans:Drug Des Devel Ther
Auteurs principaux: Yeap, SweeKeong, Akhtar, Muhammad Nadeem, Lim, Kian Lam, Abu, Nadiah, Ho, Wan Yong, Zareen, Seema, Roohani, Kiarash, Ky, Huynh, Tan, Sheau Wei, Lajis, Nordin, Alitheen, Noorjahan Banu
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2015
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338775/
https://ncbi.nlm.nih.gov/pubmed/25733816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S65468
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