Tau Reduction Prevents Disease in a Mouse Model of Dravet Syndrome

OBJECTIVE: Reducing levels of the microtubule-associated protein tau has shown promise as a potential treatment strategy for diseases with secondary epileptic features such as Alzheimer disease. We wanted to determine whether tau reduction may also be of benefit in intractable genetic epilepsies. ME...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Gheyara, Ania L, Ponnusamy, Ravikumar, Djukic, Biljana, Craft, Ryan J, Ho, Kaitlyn, Guo, Weikun, Finucane, Mariel M, Sanchez, Pascal E, Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338764/
https://ncbi.nlm.nih.gov/pubmed/25042160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24230
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