Traumatic Brain Injury Disrupts Cerebrovascular Tone Through Endothelial Inducible Nitric Oxide Synthase Expression and Nitric Oxide Gain of Function

BACKGROUND: Traumatic brain injury (TBI) has been reported to increase the concentration of nitric oxide (NO) in the brain and can lead to loss of cerebrovascular tone; however, the sources, amounts, and consequences of excess NO on the cerebral vasculature are unknown. Our objective was to elucidat...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Villalba, Nuria, Sonkusare, Swapnil K., Longden, Thomas A., Tran, Tram L., Sackheim, Adrian M., Nelson, Mark T., Wellman, George C., Freeman, Kalev
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338739/
https://ncbi.nlm.nih.gov/pubmed/25527626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001474
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