Endothelin‐1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy–Induced Pluripotent Stem Cell–Derived Cardiomyocytes

BACKGROUND: Despite the accumulating genetic and molecular investigations into hypertrophic cardiomyopathy (HCM), it remains unclear how this condition develops and worsens pathologically and clinically in terms of the genetic–environmental interactions. Establishing a human disease model for HCM wo...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Tanaka, Atsushi, Yuasa, Shinsuke, Mearini, Giulia, Egashira, Toru, Seki, Tomohisa, Kodaira, Masaki, Kusumoto, Dai, Kuroda, Yusuke, Okata, Shinichiro, Suzuki, Tomoyuki, Inohara, Taku, Arimura, Takuro, Makino, Shinji, Kimura, Kensuke, Kimura, Akinori, Furukawa, Tetsushi, Carrier, Lucie, Node, Koichi, Fukuda, Keiichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338713/
https://ncbi.nlm.nih.gov/pubmed/25389285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001263
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