Esterification of Low Density Lipoprotein Cholesterol in Human Fibroblasts and Its Absence in Homozygous Familial Hypercholesterolemia

A new mechanism is described for the cellular esterification of cholesterol derived from extra-cellular lipoproteins. Incubation of monolayers of cultured fibroblasts from normal human subjects with low density lipoproteins led to a 30- to 40-fold increase in the rate of incorporation of either [(14...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Goldstein, Joseph L., Dana, Suzanna E., Brown, Michael S.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1974
Témata:	Biological Sciences: Biochemistry
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433867/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4373706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4288
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