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Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

Testicular germ cell tumours (TGCTs) are the most common cancer in young men. Here we perform whole-exome sequencing (WES) of 42 TGCTs to comprehensively study the cancer's mutational profile. The mutation rate is uniformly low in all of the tumours (mean 0.5 mutations per Mb) as compared with...

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הוצא לאור ב:	Nat Commun
Main Authors:	Litchfield, Kevin, Summersgill, Brenda, Yost, Shawn, Sultana, Razvan, Labreche, Karim, Dudakia, Darshna, Renwick, Anthony, Seal, Sheila, Al-Saadi, Reem, Broderick, Peter, Turner, Nicholas C., Houlston, Richard S., Huddart, Robert, Shipley, Janet, Turnbull, Clare
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Publishing Group 2015
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4338546/ https://ncbi.nlm.nih.gov/pubmed/25609015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6973
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Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

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