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Extrachromosomal driver mutations in glioblastoma and low grade glioma
Alteration of the number of copies of Double Minutes (DMs) with oncogenic EGFR mutations in response to tyrosine kinase inhibitors (TKIs) is a novel adaptive mechanism of glioblastoma. Here we provide evidence that such mutations in DMs, called here Amplification-Linked Extrachromosomal Mutations (A...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4338529/ https://ncbi.nlm.nih.gov/pubmed/25471132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6690 |
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