Enrichment of CD56(dim)KIR+CD57+ highly cytotoxic NK cells in tumor infiltrated lymph nodes of melanoma patients

An important checkpoint in the progression of melanoma is the metastasis to lymph nodes. Here, to investigate the role of lymph node NK cells in disease progression, we analyze frequency, phenotype and functions of NK cells from tumor-infiltrated (TILN) and tumor-free ipsilateral lymph nodes (TFLN)...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ali, Talib Hassan, Pisanti, Simona, Ciaglia, Elena, Mortarini, Roberta, Anichini, Andrea, Garofalo, Cinzia, Tallerico, Rossana, Santinami, Mario, Gulletta, Elio, Ietto, Caterina, Galgani, Mario, Matarese, Giuseppe, Bifulco, Maurizio, Ferrone, Soldano, Colucci, Francesco, Moretta, Alessandro, Kärre, Klas, Carbone, Ennio
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338526/
https://ncbi.nlm.nih.gov/pubmed/25472612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6639
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