The α2,3-Sialyltransferase Encoded by Myxoma Virus Is a Virulence Factor that Contributes to Immunosuppression

Myxoma virus (MYXV) induces a lethal disease called Myxomatosis in European rabbits. MYXV is one of the rare viruses that encodes an α2,3-sialyltransferase through its M138L gene. In this study, we showed that although the absence of the enzyme was not associated with any in vitro deficit, the M138L...

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Udgivet i:PLoS One
Main Authors: Boutard, Bérengère, Vankerckhove, Sophie, Markine-Goriaynoff, Nicolas, Sarlet, Mickaël, Desmecht, Daniel, McFadden, Grant, Vanderplasschen, Alain, Gillet, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338283/
https://ncbi.nlm.nih.gov/pubmed/25705900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118806
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