Post-translational modification of the myxoma-virus anti-inflammatory serpin SERP-1 by a virally encoded sialyltransferase.

SERP-1 is a secreted serpin (serine-proteinase inhibitor) encoded by myxoma virus, a poxvirus pathogen of rabbits. SERP-1 is required for myxoma-virus virulence, and the purified protein has been shown to possess independent anti-inflammatory activity in animal models of restenosis and antigen-induc...

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Dettagli Bibliografici
Autori principali: Nash, P, Barry, M, Seet, B T, Veugelers, K, Hota, S, Heger, J, Hodgkinson, C, Graham, K, Jackson, R J, McFadden, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220969/
https://ncbi.nlm.nih.gov/pubmed/10749666
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