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Loss of Prolyl Carboxypeptidase in Two-Kidney, One-Clip Goldblatt Hypertensive Mice

It is well documented that angiotensin (Ang) II contributes to kidney disease progression. The protease prolyl carboxypeptidase (PRCP) is highly expressed in the kidney and may be renoprotective by degrading Ang II to Ang-(1-7). The aim of the study was to investigate whether renal PRCP protein expr...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Grobe, Nadja, Leiva, Orly, Morris, Mariana, Elased, Khalid M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338234/
https://ncbi.nlm.nih.gov/pubmed/25706121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117899
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