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Rhodopsin kinase and recoverin modulate phosphodiesterase during mouse photoreceptor light adaptation

Light stimulates rhodopsin in a retinal rod to activate the G protein transducin, which binds to phosphodiesterase (PDE), relieving PDE inhibition and decreasing guanosine 3′,5′-cyclic monophosphate (cGMP) concentration. The decrease in cGMP closes outer segment channels, producing the rod electrica...

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Bibliografski detalji
Izdano u:J Gen Physiol
Glavni autori: Chen, Ching-Kang, Woodruff, Michael L., Fain, Gordon L.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338159/
https://ncbi.nlm.nih.gov/pubmed/25667411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411273
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