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Rhodopsin kinase and recoverin modulate phosphodiesterase during mouse photoreceptor light adaptation
Light stimulates rhodopsin in a retinal rod to activate the G protein transducin, which binds to phosphodiesterase (PDE), relieving PDE inhibition and decreasing guanosine 3′,5′-cyclic monophosphate (cGMP) concentration. The decrease in cGMP closes outer segment channels, producing the rod electrica...
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| 出版年: | J Gen Physiol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4338159/ https://ncbi.nlm.nih.gov/pubmed/25667411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411273 |
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