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A TagSNP in SIRT1 Gene Confers Susceptibility to Myocardial Infarction in a Chinese Han Population

SIRT1 exerts protective effects against endothelial cells dysfunction, inflammation and atherosclerosis, indicating an important role on myocardial infarction (MI) pathogenesis. Nonetheless, the effects of SIRT1 variants on MI risk remain poorly understood. Here we aimed to investigate the influence...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Cheng, Jie, Cho, Miook, Cen, Jin-ming, Cai, Meng-yun, Xu, Shun, Ma, Ze-wei, Liu, Xinguang, Yang, Xi-li, Chen, Can, Suh, Yousin, Xiong, Xing-dong
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338141/
https://ncbi.nlm.nih.gov/pubmed/25706717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115339
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