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A TagSNP in SIRT1 Gene Confers Susceptibility to Myocardial Infarction in a Chinese Han Population

SIRT1 exerts protective effects against endothelial cells dysfunction, inflammation and atherosclerosis, indicating an important role on myocardial infarction (MI) pathogenesis. Nonetheless, the effects of SIRT1 variants on MI risk remain poorly understood. Here we aimed to investigate the influence...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cheng, Jie, Cho, Miook, Cen, Jin-ming, Cai, Meng-yun, Xu, Shun, Ma, Ze-wei, Liu, Xinguang, Yang, Xi-li, Chen, Can, Suh, Yousin, Xiong, Xing-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338141/
https://ncbi.nlm.nih.gov/pubmed/25706717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115339
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