Analysis of Cathepsin and Furin Proteolytic Enzymes Involved in Viral Fusion Protein Activation in Cells of the Bat Reservoir Host

Bats of different species play a major role in the emergence and transmission of highly pathogenic viruses including Ebola virus, SARS-like coronavirus and the henipaviruses. These viruses require proteolytic activation of surface envelope glycoproteins needed for entry, and cellular cathepsins have...

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Bibliographic Details
Published in:PLoS One
Main Authors: El Najjar, Farah, Lampe, Levi, Baker, Michelle L., Wang, Lin-Fa, Dutch, Rebecca Ellis
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338073/
https://ncbi.nlm.nih.gov/pubmed/25706132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115736
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