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Drosophila Wingless is loaded on exosome-like vesicles but forms a gradient in an exosome-independent manner

Wingless acts as a morphogen in Drosophila wing discs, where it specifies cell fates and controls growth several cell diameters away from its site of expression. Thus, despite being acylated and membrane-associated, Wingless spreads in the extracellular space. Recent studies have focussed on identif...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Beckett, Karen, Monier, Solange, Palmer, Lucy, Alexandre, Cyrille, Green, Hannah, Bonneil, Eric, Raposo, Graca, Thibault, Pierre, Le Borgne, Roland, Vincent, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337976/
https://ncbi.nlm.nih.gov/pubmed/23035643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12016
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