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Godzilla-dependent transcytosis promotes Wingless signalling in Drosophila wing imaginal discs

The apical and basolateral membranes of epithelia are insulated from each other, preventing the transfer of extracellular proteins from one side to the other(1). Thus, a signalling protein produced apically is not expected to reach basolateral receptors. Evidence suggests that Wingless, the main Dro...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Yamazaki, Yasuo, Palmer, Lucy, Alexandre, Cyrille, Kakugawa, Satoshi, Beckett, Karen, Gaugue, Isabelle, Palmer, Ruth H., Vincent, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817240/
https://ncbi.nlm.nih.gov/pubmed/26974662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3325
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