Suppression of Human Glioma Xenografts with Second-Generation IL13R-Specific Chimeric Antigen Receptor–Modified T Cells

PURPOSE: Glioblastoma multiforme (GBM) remains highly incurable, with frequent recurrences after standard therapies of maximal surgical resection, radiation, and chemotherapy. To address the need for new treatments, we have undertaken a chimeric antigen receptor (CAR) “designer T cell” (dTc) immunot...

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Pubblicato in:Clin Cancer Res
Autori principali: Kong, Seogkyoung, Sengupta, Sadhak, Tyler, Betty, Bais, Anthony J., Ma, Qiangzhong, Doucette, Saryn, Zhou, Jinyuan, Sahin, Ayguen, Carter, Bob S., Brem, Henry, Junghans, Richard P., Sampath, Prakash
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337849/
https://ncbi.nlm.nih.gov/pubmed/22966020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0319
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