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Pharmacological profiles of the murine gastric and colonic H,K-ATPases

BACKGROUND: The H,K-ATPase, consisting of α and β subunits, belongs to the P-type ATPase family. There are two isoforms of the α subunit, HKα(1) and HKα(2) encoded by different genes. The ouabain-resistant gastric HKα(1)-H,K-ATPase is Sch28080-sensitive. However, the colonic HKα(2)-H,K-ATPase from d...

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Publicado en:Biochim Biophys Acta
Autores principales: Shao, Jiahong, Gumz, Michelle L., Cain, Brian D., Xia, Shen-Ling, Shull, Gary E., van Driel, Ian R., Wingo, Charles S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337798/
https://ncbi.nlm.nih.gov/pubmed/20594946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2010.05.002
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