Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice.

Previous studies using isolated tissues suggest that the colonic H, K-ATPase (cHKA), expressed in the colon and kidney, plays an important role in K+ conservation. To test the role of this pump in K+ homeostasis in vivo, we generated a cHKA-deficient mouse and analyzed its ability to retain K+ when...

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Main Authors: Meneton, P, Schultheis, P J, Greeb, J, Nieman, M L, Liu, L H, Clarke, L L, Duffy, J J, Doetschman, T, Lorenz, J N, Shull, G E
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508595/
https://ncbi.nlm.nih.gov/pubmed/9449685
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