Angiomotin functions in HIV-1 assembly and budding

Many retroviral Gag proteins contain PPXY late assembly domain motifs that recruit proteins of the NEDD4 E3 ubiquitin ligase family to facilitate virus release. Overexpression of NEDD4L can also stimulate HIV-1 release but in this case the Gag protein lacks a PPXY motif, suggesting that NEDD4L may f...

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Bibliographic Details
Published in:eLife
Main Authors: Mercenne, Gaelle, Alam, Steven L, Arii, Jun, Lalonde, Matthew S, Sundquist, Wesley I
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2015
Subjects:
Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337731/
https://ncbi.nlm.nih.gov/pubmed/25633977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03778
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