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Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein

The hemispheric, bi-layered optic cup forms from an oval optic vesicle during early vertebrate eye development through major morphological transformations. The overall basal surface, facing the developing lens, is increasing, while, at the same time, the space basally occupied by individual cells is...

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Bibliographic Details
Published in:eLife
Main Authors: Heermann, Stephan, Schütz, Lucas, Lemke, Steffen, Krieglstein, Kerstin, Wittbrodt, Joachim
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337729/
https://ncbi.nlm.nih.gov/pubmed/25719386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05216
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