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TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism

The optic fissure is a transient gap in the developing vertebrate eye, which must be closed as development proceeds. A persisting optic fissure, coloboma, is a major cause for blindness in children. Although many genes have been linked to coloboma, the process of optic fissure fusion is still little...

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Publicat a:Open Biol
Autors principals: Knickmeyer, Max D., Mateo, Juan L., Eckert, Priska, Roussa, Eleni, Rahhal, Belal, Zuniga, Aimee, Krieglstein, Kerstin, Wittbrodt, Joachim, Heermann, Stephan
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881030/
https://ncbi.nlm.nih.gov/pubmed/29593116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.170134
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