Interaction between positive allosteric modulators and trapping blockers of the NMDA receptor channel

BACKGROUND AND PURPOSE: Memantine and ketamine are clinically used, open-channel blockers of NMDA receptors exhibiting remarkable pharmacodynamic similarities despite strikingly different clinical profiles. Although NMDA channel gating constitutes an important difference between memantine and ketami...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Emnett, Christine M, Eisenman, Lawrence N, Mohan, Jayaram, Taylor, Amanda A, Doherty, James J, Paul, Steven M, Zorumski, Charles F, Mennerick, Steven
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2015
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337705/
https://ncbi.nlm.nih.gov/pubmed/25377730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13007
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