The phytocannabinoid, Δ(9)-tetrahydrocannabivarin, can act through 5-HT(1A) receptors to produce antipsychotic effects

BACKGROUND AND PURPOSE: This study aimed to address the questions of whether Δ(9)-tetrahydrocannabivarin (THCV) can (i) enhance activation of 5-HT(1)(A) receptors in vitro and (ii) induce any apparent 5-HT(1)(A) receptor-mediated antipsychotic effects in vivo. EXPERIMENTAL APPROACH: In vitro studies...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Cascio, Maria Grazia, Zamberletti, Erica, Marini, Pietro, Parolaro, Daniela, Pertwee, Roger G
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337703/
https://ncbi.nlm.nih.gov/pubmed/25363799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13000
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