Population pharmacokinetics of pegaptanib sodium (Macugen(®)) in patients with diabetic macular edema

OBJECTIVE: Population pharmacokinetic modeling of pegaptanib was undertaken to determine influence of renal function on apparent clearance. METHODS: In a randomized, double-masked multicenter trial, intravitreal pegaptanib (0.3, 1.0, or 3.0 mg/eye) was administered in patients with diabetic macular...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Ophthalmol
Main Authors: Basile, Anthony S, Hutmacher, Matthew M, Kowalski, Kenneth G, Gandelman, Kuan Y, Nickens, Dana J
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337691/
https://ncbi.nlm.nih.gov/pubmed/25733800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S74050
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