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Population pharmacokinetics of pegaptanib sodium (Macugen(®)) in patients with diabetic macular edema
OBJECTIVE: Population pharmacokinetic modeling of pegaptanib was undertaken to determine influence of renal function on apparent clearance. METHODS: In a randomized, double-masked multicenter trial, intravitreal pegaptanib (0.3, 1.0, or 3.0 mg/eye) was administered in patients with diabetic macular...
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| Publicado no: | Clin Ophthalmol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337691/ https://ncbi.nlm.nih.gov/pubmed/25733800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S74050 |
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