Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD

Type III secretion systems (T3SS) translocate effector proteins into target cells in order to disrupt or modulate host cell signaling pathways and establish replicative niches. However, recognition of T3SS activity by cytosolic pattern recognition receptors (PRRs) of the nucleotide-binding domain le...

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Bibliographic Details
Published in:mBio
Main Authors: Zwack, Erin E., Snyder, Annelise G., Wynosky-Dolfi, Meghan A., Ruthel, Gordon, Philip, Naomi H., Marketon, Melanie M., Francis, Matthew S., Bliska, James B., Brodsky, Igor E.
Format: Artigo
Language:Inglês
Published: American Society of Microbiology 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337566/
https://ncbi.nlm.nih.gov/pubmed/25691590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02095-14
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