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Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD

Type III secretion systems (T3SS) translocate effector proteins into target cells in order to disrupt or modulate host cell signaling pathways and establish replicative niches. However, recognition of T3SS activity by cytosolic pattern recognition receptors (PRRs) of the nucleotide-binding domain le...

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Detalles Bibliográficos
Publicado en:mBio
Main Authors: Zwack, Erin E., Snyder, Annelise G., Wynosky-Dolfi, Meghan A., Ruthel, Gordon, Philip, Naomi H., Marketon, Melanie M., Francis, Matthew S., Bliska, James B., Brodsky, Igor E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337566/
https://ncbi.nlm.nih.gov/pubmed/25691590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02095-14
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