Overlapping Local and Long-Range RNA-RNA Interactions Modulate Dengue Virus Genome Cyclization and Replication

The dengue virus genome is a dynamic molecule that adopts different conformations in the infected cell. Here, using RNA folding predictions, chemical probing analysis, RNA binding assays, and functional studies, we identified new cis-acting elements present in the capsid coding sequence that facilit...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: de Borba, Luana, Villordo, Sergio M., Iglesias, Nestor G., Filomatori, Claudia V., Gebhard, Leopoldo G., Gamarnik, Andrea V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337542/
https://ncbi.nlm.nih.gov/pubmed/25589642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02677-14
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