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Contribution of MxB Oligomerization to HIV-1 Capsid Binding and Restriction
The alpha interferon (IFN-α)-inducible restriction factor myxovirus B (MxB) blocks HIV-1 infection after reverse transcription but prior to integration. MxB binds to the HIV-1 core, which is composed of capsid protein, and this interaction leads to inhibition of the uncoating process of HIV-1. Previ...
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| Pubblicato in: | J Virol |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337540/ https://ncbi.nlm.nih.gov/pubmed/25568212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03730-14 |
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