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Guanosine 3′:5′-Cyclic Monophosphate and the Action of Insulin and Acetylcholine

Low concentrations of insulin (120 μunits/ml) and of carbamylcholine (1 μM) increase cyclic GMP content in isolated fat cells by 350%. The maximal amount of cyclic GMP, achieved within 2 min after addition of insulin or carbamylcholine, falls rapidly for insulin and much more slowly for carbamylchol...

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Bibliographic Details
Main Authors: Illiano, Gennaro, Tell, Guy P. E., Siegel, Marvin I., Cuatrecasas, Pedro
Format: Artigo
Language:Inglês
Published: 1973
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC433753/
https://ncbi.nlm.nih.gov/pubmed/4365701
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