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Lambda-Chain Production in Human Lymphoblast-Mouse Fibroblast Hybrids

Mutant human lymphoblast cells deficient in hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) activity were hybridized with thymidine kinase (EC 2.7.1.21)-deficient mouse fibroblasts. Hybrid cells were readily selected, as both parental lines were nonreverting and eliminated by hypoxanthine-ametho...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Orkin, Stuart H., Buchanan, Philip D., Yount, William J., Reisner, Howard, Littlefield, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1973
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433744/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4599625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.8.2401
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