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Lambda-Chain Production in Human Lymphoblast-Mouse Fibroblast Hybrids

Mutant human lymphoblast cells deficient in hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) activity were hybridized with thymidine kinase (EC 2.7.1.21)-deficient mouse fibroblasts. Hybrid cells were readily selected, as both parental lines were nonreverting and eliminated by hypoxanthine-ametho...

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Detalhes bibliográficos
Main Authors: Orkin, Stuart H., Buchanan, Philip D., Yount, William J., Reisner, Howard, Littlefield, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC433744/
https://ncbi.nlm.nih.gov/pubmed/4599625
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