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Kinetic and Spectroscopic Evidence of Negative Cooperativity in the Action of Lysine 2,3-Aminomutase()

Lysine 2,3-aminomutase (LAM) catalyzes the interconversion of L-lysine and L-β-lysine, a component of a number of antibiotics. The reaction requires the cofactors S-adenosyl-L-methionine (SAM), pyridoxal-5′-phosphate (PLP), and a [4Fe–4S] cluster. LAM is a founding member of the Radical SAM superfam...

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Bibliografske podrobnosti
izdano v:J Phys Chem B
Main Authors: Ruzicka, Frank J., Frey, Perry A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337230/
https://ncbi.nlm.nih.gov/pubmed/20608698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp103856m
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