Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

18 Carcinogens, including aflatoxin B(1), benzo(a)pyrene, acetylaminofluorene, benzidine, and dimethylamino-trans-stilbene, are shown to be activated by liver homogenates to form potent frameshift mutagens. We believe that these carcinogens have in common a ring system sufficiently planar for a stac...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ames, Bruce N., Durston, William E., Yamasaki, Edith, Lee, Frank D.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1973
Schlagworte:	Biological Sciences: Genetics
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4151811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.8.2281
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