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Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

18 Carcinogens, including aflatoxin B(1), benzo(a)pyrene, acetylaminofluorene, benzidine, and dimethylamino-trans-stilbene, are shown to be activated by liver homogenates to form potent frameshift mutagens. We believe that these carcinogens have in common a ring system sufficiently planar for a stac...

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Détails bibliographiques
Auteurs principaux: Ames, Bruce N., Durston, William E., Yamasaki, Edith, Lee, Frank D.
Format: Artigo
Langue:Inglês
Publié: 1973
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC433718/
https://ncbi.nlm.nih.gov/pubmed/4151811
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