ERG Oncoprotein Inhibits ANXA2 Expression and Function in Prostate Cancer

Overexpression of ERG in the prostate epithelium, due to chromosomal translocations, contributes to prostate tumorigenesis. Here, analysis of ERG siRNA-treated prostate cells harboring the endogenous TMPRSS2-ERG fusion revealed an inverse relationship between ERG and Annexin A2 (ANXA2) expression at...

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Gepubliceerd in:Mol Cancer Res
Hoofdauteurs: Griner, Nicholas B., Young, Denise, Chaudhary, Pankaj, Mohamed, Ahmed A., Huang, Wei, Chen, Yongmei, Sreenath, Taduru, Dobi, Albert, Petrovics, Gyorgy, Vishwanatha, Jamboor K., Sesterhenn, Isabell A, Srivastava, Shiv, Tan, Shyh-Han
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336823/
https://ncbi.nlm.nih.gov/pubmed/25344575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0275-T
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