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Peptide-Based, Two-Fluorophore, Ratiometric Probe for Quantifying Mobile Zinc in Biological Solutions

[Image: see text] Small-molecule fluorescent sensors are versatile agents for detecting mobile zinc in biology. Capitalizing on the abundance of validated mobile zinc probes, we devised a strategy for repurposing existing intensity-based sensors for quantitative applications. Using solid-phase pepti...

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Pubblicato in:ACS Chem Biol
Autori principali: Zhang, Daniel Y., Azrad, Maria, Demark-Wahnefried, Wendy, Frederickson, Christopher J., Lippard, Stephen J., Radford, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336589/
https://ncbi.nlm.nih.gov/pubmed/25382858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500617c
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