Improved Sensitivity for Imaging Spin Trapped Hydroxyl Radical at 250 MHz

Radicals, including hydroxyl, superoxide, and nitric oxide, play key signaling roles in vivo. Reaction of these free radicals with a spin trap affords more stable paramagnetic nitroxides, but concentrations in vivo still are so low that detection by electron paramagnetic resonance (EPR) is challengi...

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Veröffentlicht in:Chemphyschem
Hauptverfasser: Biller, Joshua R., Tseitlin, Mark, Mitchell, Deborah G., Yu, Zhelin, Buchanan, Laura A., Elajaili, Hanan, Rosen, Gerald M., Kao, Joseph P. Y., Eaton, Sandra S., Eaton, Gareth R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336543/
https://ncbi.nlm.nih.gov/pubmed/25488257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.201402835
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