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Restoration of Hypoxanthine Phosphoribosyl Transferase Activity in Mouse 1R Cells After Fusion with Chick-Embryo Fibroblasts

Fusion of the 1R mouse cell, which lacks activity of hypoxanthine phosphoribosyl transferase (EC 2.4.2.8), with chick-embryo fibroblasts yielded progeny cells that survived in hypoxanthine-aminopterin-thymidine selective medium. This property and the failure of the progeny to survive in 8-azaguanine...

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Autors principals: Bakay, Bohdan, Croce, Carlo M., Koprowski, Hilary, Nyhan, William L.
Format: Artigo
Idioma:Inglês
Publicat: 1973
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC433651/
https://ncbi.nlm.nih.gov/pubmed/4516198
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