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Quantifying the Entropy of Binding for Water Molecules in Protein Cavities by Computing Correlations

Protein structural analysis demonstrates that water molecules are commonly found in the internal cavities of proteins. Analysis of experimental data on the entropies of inorganic crystals suggests that the entropic cost of transferring such a water molecule to a protein cavity will not typically be...

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Detalhes bibliográficos
Publicado no:Biophys J
Autor principal: Huggins, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336375/
https://ncbi.nlm.nih.gov/pubmed/25692597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.035
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