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Thermodynamic Properties of Water Molecules at a Protein–Protein Interaction Surface

Protein–protein interactions (PPIs) have been identified as a vital regulator of cellular pathways and networks. However, the determinants that control binding affinity and specificity at protein surfaces are incompletely characterized and thus unable to be exploited for the purpose of developing PP...

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Detalhes bibliográficos
Main Authors: Huggins, David J., Marsh, May, Payne, Mike C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924879/
https://ncbi.nlm.nih.gov/pubmed/24554921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct200465z
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