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Simulating the Entropic Collapse of Coarse-Grained Chromosomes

Depletion forces play a role in the compaction and decompaction of chromosomal material in simple cells, but it has remained debatable whether they are sufficient to account for chromosomal collapse. We present coarse-grained molecular dynamics simulations, which reveal that depletion-induced attrac...

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Publicat a:Biophys J
Autors principals: Shendruk, Tyler N., Bertrand, Martin, de Haan, Hendrick W., Harden, James L., Slater, Gary W.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336370/
https://ncbi.nlm.nih.gov/pubmed/25692586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3487
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