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Human Adenosine A2A Receptor Binds Calmodulin with High Affinity in a Calcium-Dependent Manner

Understanding how ligands bind to G-protein-coupled receptors and how binding changes receptor structure to affect signaling is critical for developing a complete picture of the signal transduction process. The adenosine A2A receptor (A2AR) is a particularly interesting example, as it has an excepti...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Piirainen, Henni, Hellman, Maarit, Tossavainen, Helena, Permi, Perttu, Kursula, Petri, Jaakola, Veli-Pekka
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336363/
https://ncbi.nlm.nih.gov/pubmed/25692595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.036
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