Novel Receptor-Derived Cyclopeptides to Treat Heart Failure Caused by Anti-β(1)-Adrenoceptor Antibodies in a Human-Analogous Rat Model

Despite recent therapeutic advances the prognosis of heart failure remains poor. Recent research suggests that heart failure is a heterogeneous syndrome and that many patients have stimulating auto-antibodies directed against the second extracellular loop of the β(1) adrenergic receptor (β(1)EC2). I...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Boivin, Valérie, Beyersdorf, Niklas, Palm, Dieter, Nikolaev, Viacheslav O., Schlipp, Angela, Müller, Justus, Schmidt, Doris, Kocoski, Vladimir, Kerkau, Thomas, Hünig, Thomas, Ertl, Georg, Lohse, Martin J., Jahns, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336331/
https://ncbi.nlm.nih.gov/pubmed/25700031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117589
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