Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure

RATIONALE: Despite advances in pharmacotherapy, heart failure still incurs significant morbidity and mortality. Stimulating antibodies directed against the secondextracellular loop of the human ß(1)-adrenergic receptor (anti-ß(1)EC2) cause myocyte damage and heart failure in rats. This receptor doma...

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Vydáno v:PLoS One
Hlavní autoři: Boivin-Jahns, Valérie, Uhland, Kerstin, Holthoff, Hans-Peter, Beyersdorf, Niklas, Kocoski, Vladimir, Kerkau, Thomas, Münch, Götz, Lohse, Martin J., Ungerer, Martin, Jahns, Roland
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101361/
https://ncbi.nlm.nih.gov/pubmed/30125285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201160
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