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Herpes Simplex Virus as a Source of Thymidine Kinase for Thymidine Kinase-Deficient Mouse Cells: Suppression and Reactivation of the Viral Enzyme

Thymidine kinase (EC 2.7.1.21)-deficient mouse cells were infected with inactivated herpes simplex virus, after which “transformed” cells that produce viral thymidine kinase were isolated. Shortly after transformation, the expression of the viral enzyme could be suppressed and reactivated with high...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Davidson, Richard L., Adelstein, S. J., Oxman, Michael N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1973
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433631/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4352962/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.7.1912
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